Phenotypes Associated with This Genotype

Genotype
MGI:3619121

• Allelic Composition: Agt^tm1Unc/Agt⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating angiotensinogen level ( J:18272 , J:24156 )

• have 35% of the level of angiotensinogen seen in wild-type (J:18272)

increased circulating renin level ( J:24156 )

• renin levels are 250% of normal levels

cardiovascular system

increased renal plasma flow rate ( J:24156 )

decreased systemic arterial blood pressure ( J:24156 )

renal/urinary system

renal/urinary system phenotype ( J:24156 )

N • kidneys and glomerular filtration rate are normal

increased renal plasma flow rate ( J:24156 )

reproductive system

reproductive system phenotype ( J:24156 )

N • do not exhibit a defect in ovulatory capacity is response to superovulation