About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3618695
Allelic
Composition
Tg(TcrbAI4)1Dvs/0
Genetic
Background
NOD-Tg(TcrbAI4)1Dvs
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(TcrbAI4)1Dvs mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• T cells expressing the transgene comprise ~22% of the total peripheral blood lymphocyte population, a significantly higher fraction of these T cells resides in the CD4 lineage rather than in the expected CD8 lineage

homeostasis/metabolism
• female NOD mice carrying this transgene exhibit a significantly reduced frequency and rate of development of IDDM

immune system
• T cells expressing the transgene comprise ~22% of the total peripheral blood lymphocyte population, a significantly higher fraction of these T cells resides in the CD4 lineage rather than in the expected CD8 lineage

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:93553


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory