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Phenotypes Associated with This Genotype
Genotype
MGI:3618584
Allelic
Composition		 Cdkn1btm1Mlf/Cdkn1b+
Crebbptm1Jvd/Crebbptm1Jvd
Tg(MMTV-cre)4Mam/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1btm1Mlf mutation (2 available); any Cdkn1b mutation (26 available)
Crebbptm1Jvd mutation (2 available); any Crebbp mutation (100 available)
Tg(MMTV-cre)4Mam mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased T cell derived lymphoma incidence ( J:88323 )
• considerably accelerated tumor development

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:88323 )
• considerably accelerated tumor development

hematopoietic system
increased T cell derived lymphoma incidence ( J:88323 )
• considerably accelerated tumor development

immune system
increased T cell derived lymphoma incidence ( J:88323 )
• considerably accelerated tumor development

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory