Phenotypes Associated with This Genotype

Genotype
MGI:3618306

• Allelic Composition: Dclk1^tm1.1Jgg/Dclk1^tm1.1Jgg
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon guidance ( J:105300 )

• corpus callosum axonal projections are disrupted; decussation of interhemispheric corpus callosal axons is abnormal and axons fail to cross the midline

abnormal corpus callosum morphology ( J:105300 )

• Probst bundles are present in mutants

absent corpus callosum ( J:105300 )

• homozygous mice display an absence of the corpus callosum

absent hippocampal commissure ( J:105300 )

• hippocampal commissure is absent

cellular

abnormal axon guidance ( J:105300 )

• corpus callosum axonal projections are disrupted; decussation of interhemispheric corpus callosal axons is abnormal and axons fail to cross the midline