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Phenotypes Associated with This Genotype
Genotype
MGI:3618279
Allelic
Composition		 Apoetm1Unc/Apoetm1Unc
Cx3cr1tm1Zm/Cx3cr1+
Genetic
Background		 B6.129-Apoetm1Unc Cx3cr1tm1Zm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (35 available); any Apoe mutation (164 available)
Cx3cr1tm1Zm mutation (1 available); any Cx3cr1 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased susceptibility to atherosclerosis ( J:103047 )
• lesion area in the thoracic aorta is decreased by about 50% compared to mice homozygous for the Apoe allele only

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory