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Phenotypes Associated with This Genotype
Genotype
MGI:3618178
Allelic
Composition		 Adamts5tm1Lex/Adamts5tm1Lex
Tg(CMV-cre)1Cgn/0
Genetic
Background		 involves: 129S5/SvEvBrd * BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts5tm1Lex mutation (2 available); any Adamts5 mutation (54 available)
Tg(CMV-cre)1Cgn mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
osteoarthritis ( J:105138 )
• protected against inflammatory arthritis
• otherwise viable, fertile, and phenotypically normal

immune system
osteoarthritis ( J:105138 )
• protected against inflammatory arthritis
• otherwise viable, fertile, and phenotypically normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory