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Phenotypes Associated with This Genotype
Genotype
MGI:3617976
Allelic
Composition
Stat4tm1Gru/Stat4+
Genetic
Background
NOD.129S2-Stat4tm1Gru
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat4tm1Gru mutation (4 available); any Stat4 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• a significant decrease in the incidence of diabetes (30%) is observed compared with wild-type Stat4 NOD mice (74%); diabetes is diagnosed when 3 blood glucose measures are equal to or higher than 13.9 mmol/l

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
type 1 diabetes mellitus DOID:9744 OMIM:222100
J:90600


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory