Phenotypes Associated with This Genotype

Genotype
MGI:3617780

• Allelic Composition: Gab1^tm1Wbm/Gab1^tm1Wbm
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal muscle precursor cell migration ( J:100909 )

• at E10.75 fewer hypaxial muscle progenitor cells reach the floor of the first branchial arch

abnormal intrinsic tongue muscle morphology ( J:100909 )

• the intrinsic tongue muscle is smaller but present

hypaxial muscle hypoplasia ( J:100909 )

• limb muscle size is reduced and in the proximal portion of the lower forelimb, particular extensor muscles of dorsal limb are reduced in size

digestive/alimentary system

abnormal intrinsic tongue muscle morphology ( J:100909 )

• the intrinsic tongue muscle is smaller but present

craniofacial

abnormal intrinsic tongue muscle morphology ( J:100909 )

• the intrinsic tongue muscle is smaller but present

cellular

abnormal muscle precursor cell migration ( J:100909 )

• at E10.75 fewer hypaxial muscle progenitor cells reach the floor of the first branchial arch

growth/size/body

abnormal intrinsic tongue muscle morphology ( J:100909 )

• the intrinsic tongue muscle is smaller but present