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Phenotypes Associated with This Genotype
Genotype
MGI:3617775
Allelic
Composition		 Gab1tm1Wbm/Gab1+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab1tm1Wbm mutation (0 available); any Gab1 mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:68751 )
• about 5% of heterozygotes develop after spasms 2-3 months of age and die

behavior/neurological
abnormal behavior ( J:68751 )
• about 5% of heterozygotes develop after spasms 2-3 months of age and die

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory