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Phenotypes Associated with This Genotype
Genotype
MGI:3617392
Allelic
Composition
Pkd1tm2Ggg/Pkd1tm2Ggg
Tg(MMTV-cre)4Mam/0
Genetic
Background
involves: 129S4/SvJae * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2Ggg mutation (1 available); any Pkd1 mutation (68 available)
Tg(MMTV-cre)4Mam mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• 60% exhibit an occasional cyst on the surface of the kidney at 10 weeks of age and 100% have kidney cysts at 20 weeks of age

liver/biliary system
• 20% exhibit an occasional cyst on the surface of the liver at 10 weeks of age and 100% have multiple hepatic cysts at 20 weeks of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Polycystic Kidney Disease 1; PKD1 173900 J:103719


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory