Phenotypes Associated with This Genotype

Genotype
MGI:3616464

• Allelic Composition: Del(2Hoxd10)13Ddu/Del(2Hoxd10)13Ddu
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal gait ( J:103924 )

• retain left-right alternation in waliking

• foot placement and gait similar to clubfoot phenotypes

hindlimb paralysis ( J:103924 )

• distally restricted leg paralysis

• could bear body weight on hind legs

nervous system

abnormal spinal nerve morphology ( J:103924 )

• thinner or shorter peroneal nerve at E12.5 and E13.5

• peroneal branch absent in adults

• all lumbo-sacral spinal roots transformed and as a result one thoracic root is lost