Phenotypes for Nbn Rad50 MGI:3615682 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nbn^tm1Jpt/Nbn⁺ Rad50^tm2Jpt/Rad50^tm2Jpt
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nbn^tm1Jpt mutation (1 available); any Nbn mutation (59 available)
Rad50^tm2Jpt mutation (0 available); any Rad50 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:103922 )

N	• exhibit hematopoietic rescue of the abnormalities seen in homozygous Rad50^tm2Jpt mice, with numbers of double-negative T cells, pro-B cells, and macrophages within 5-fold levels of wild-type levels

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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