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Phenotypes Associated with This Genotype
Genotype
MGI:3615446
Allelic
Composition
Polhtm1.1Rak/Polh+
Genetic
Background
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polhtm1.1Rak mutation (0 available); any Polh mutation (36 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• increased incidence several months after UV-irradiation
• increased susceptibility over wild-type to develop skin tumors

integument
• increased susceptibility over wild-type to develop skin tumors

homeostasis/metabolism
• increased incidence several months after UV-irradiation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
01/13/2026
MGI 6.24
The Jackson Laboratory