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Phenotypes Associated with This Genotype
Genotype
MGI:3614439
Allelic
Composition
Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kiss1rtm1Gstn mutation (0 available); any Kiss1r mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• examination of homozygous embryos at 16.5 dpc shows no differences in the development of the reproductive organs compared to wild-type suggesting that the appearance of the following phenotypes at 7 weeks of age is a postnatal event (J:102113)
• examination of homozygous embryos at 16.5 dpc shows no differences in the development of the reproductive organs compared to wild-type suggesting that the appearance of the following phenotypes at 7 weeks of age is a postnatal event (J:102113)
(J:102113)
(J:102113)
• reduced in size or not found due to small size (J:102113)
• reduced in size or not found due to small size (J:102113)
(J:102113)
(J:102113)
• hypoplasia of uterine horns (J:102113)
• hypoplasia of uterine horns (J:102113)
• reduced in size or not found due to small size (J:102113)
• reduced in size or not found due to small size (J:102113)
• frequently absent (J:102113)
• frequently absent (J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
• 17% reduction in testis weight (J:102113)
• 17% reduction in testis weight (J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)

growth/size/body
• males exhibit lower body weight than controls (J:102113)
• males exhibit lower body weight than controls (J:102113)

immune system
• higher thymus/body weight ratio (J:102113)
• higher thymus/body weight ratio (J:102113)

renal/urinary system
• frequently absent (J:102113)
• frequently absent (J:102113)
• reduced kidney/body weight ratio (J:102113)
• reduced kidney/body weight ratio (J:102113)
(J:102113)
(J:102113)

endocrine/exocrine glands
• higher thymus/body weight ratio (J:102113)
• higher thymus/body weight ratio (J:102113)
(J:102113)
(J:102113)
• frequently absent (J:102113)
• frequently absent (J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
(J:102113)
• 17% reduction in testis weight (J:102113)
• 17% reduction in testis weight (J:102113)

hematopoietic system
• higher thymus/body weight ratio (J:102113)
• higher thymus/body weight ratio (J:102113)

integument
(J:102113)
(J:102113)
• frequently absent (J:102113)
• frequently absent (J:102113)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory