Mouse Genome Informatics
hm
    Kiss1rtm1Gstn/Kiss1rtm1Gstn
involves: 129P2/OlaHsd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
reproductive system
N
• examination of homozygous embryos at 16.5 dpc shows no differences in the development of the reproductive organs compared to wild-type suggesting that the appearance of the following phenotypes at 7 weeks of age is a postnatal event (J:102113)
(J:102113)
• reduced in size or not found due to small size (J:102113)
(J:102113)
• hypoplasia of uterine horns (J:102113)
• reduced in size or not found due to small size (J:102113)
• frequently absent (J:102113)
• 17% reduction in testis weight (J:102113)
(J:102113)
(J:102113)
(J:102113)

growth/size/body
• males exhibit lower body weight than controls

immune system
• higher thymus/body weight ratio

renal/urinary system
• frequently absent (J:102113)
• reduced kidney/body weight ratio
(J:102113)

endocrine/exocrine glands
• frequently absent (J:102113)
(J:102113)
• 17% reduction in testis weight (J:102113)
• higher thymus/body weight ratio

hematopoietic system
• higher thymus/body weight ratio

integument
• frequently absent (J:102113)

Mouse Models of Human Disease
OMIM IDRef(s)
Hypogonadotropic Hypogonadism 8 with or without Anosmia; HH8 614837 J:102113