Phenotypes for Gli2 Gli3 MGI:3614413 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gli2^tm1Alj/Gli2⁺ Gli3^Xt-J/Gli3^Xt-J
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli2^tm1Alj mutation (0 available); any Gli2 mutation (173 available)
Gli3^Xt-J mutation (3 available); any Gli3 mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal skeleton morphology ( J:38381 )

• show an enhancement of the Gli3 null phenotype

polyphalangy ( J:38381 )

fusion of vertebral arches ( J:38381 )

• neural arches of other cervical vertebrae are fused in addition to the fusion of the C1 and C2 neural arches

limbs/digits/tail

polyphalangy ( J:38381 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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