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Phenotypes Associated with This Genotype
Genotype
MGI:3613782
Allelic
Composition		 Sim1tm1Fan/Sim1+
Sim2tm1Fan/Sim2tm1Fan
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sim1tm1Fan mutation (0 available); any Sim1 mutation (52 available)
Sim2tm1Fan mutation (0 available); any Sim2 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nervous system tract morphology ( J:104419 )
• at E18.5, the principal mammillary axonal tract appears less prominent similar to mice homozygous for Sim1tm1Fan alone

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory