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Phenotypes Associated with This Genotype
Genotype
MGI:3613565
Allelic
Composition
Eportm1Hwu/Eportm1Hwu
Tg(GFAP-cre)25Mes/?
Genetic
Background
involves: 129 * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eportm1Hwu mutation (0 available); any Epor mutation (30 available)
Tg(GFAP-cre)25Mes mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• subventricular zone decreased in volume and with fewer cells although the overall brain architecture of the cortex, olfactory bulbs and cerebellum is normal
• reduced cell proliferation at age 15 days with still greater reduction at 6 months of age
• infarct size from stroke not affected, contrary to expectations due to the neuroprotective effects of exogenous erythropoietin


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory