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Phenotypes Associated with This Genotype
Genotype
MGI:3613520
Allelic
Composition
Rhoctm1Mak/Rhoctm1Mak
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhoctm1Mak mutation (1 available); any Rhoc mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• no abnormalities in T or B cell numbers or supopoulation ratios are seen
• no abnormalities in T or B cell activation are seen
• no differences in T cell or thymocyte apoptosis are seen
• cell morphology and motility of thymocytes, T cells, B cells and neutrophils are similar to controls

cellular
• fibroblasts from mutant mice exhibit decrease in stress fiber formation in response to serum starvation
• no obvious differences are seen under normal conditions


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory