About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3613468
Allelic
Composition		 Aqp5tm1Ask/Aqp5tm1Ask
Aqp8tm1Ask/Aqp8tm1Ask
Genetic
Background		 involves: 129/Sv * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp5tm1Ask mutation (0 available); any Aqp5 mutation (21 available)
Aqp8tm1Ask mutation (0 available); any Aqp8 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
decreased salivation ( J:104681 )
• saliva secretion is reduced to the same extent as in single homozygous Aqp5 mice

endocrine/exocrine glands
decreased salivation ( J:104681 )
• saliva secretion is reduced to the same extent as in single homozygous Aqp5 mice

homeostasis/metabolism
decreased salivation ( J:104681 )
• saliva secretion is reduced to the same extent as in single homozygous Aqp5 mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory