Phenotypes for Ctnnb1 Otx2 MGI:3612484 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm2.1Kem/Ctnnb1⁺ Otx2^{tm1(Dkk1)Imat}/Otx2^{tm1(Dkk1)Imat}
Genetic Background	involves: 129/Sv * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm2.1Kem mutation (0 available); any Ctnnb1 mutation (51 available)
Otx2^{tm1(Dkk1)Imat} mutation (0 available); any Otx2 mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal rostral-caudal axis patterning ( J:103272 )

• based on expression of anterior visceral endoderm markers, the anterior migration defects of distal visceral endoderm cells observed in 6.5 p.d.c. Otx2^tm2/Otx2^tm2 embryo was partially rescued

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24