Phenotypes Associated with This Genotype

Genotype
MGI:3612398

• Allelic Composition: Gria2^tm3Rsp/Gria2^tm3Rsp; Tg(Camk2a-cre)1Gsc/0
• Genetic Background: involves: C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal learning/memory/conditioning ( J:103689 )

• exhibit decreased olfactory memory

abnormal olfactory discrimination memory ( J:103689 )

• exhibit more rapid odor learning and enhanced olfactory discrimination in a go/no-go operant conditioning task, and decreased olfactory memory

increased exploration in new environment ( J:103689 )

• exploratory behavior in an open field task is slightly increased

abnormal spatial learning ( J:103689 )

• acquisition of a nonolfactory hippocampus-dependent spatial learning task (elevated Y-maze) is slightly impaired

increased anxiety-related response ( J:103689 )

• dark/light box tests reveal increased anxiety

impaired coordination ( J:103689 )

• motor coordination in an accelerating rotarod is somewhat impaired