Phenotypes Associated with This Genotype

Genotype
MGI:3612126

• Allelic Composition: Smarcad1^tm1Gos/Smarcad1⁺
• Genetic Background: involves: 129S2/SvPas * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal axial skeleton morphology ( J:56661 )

• Background Sensitivity: on a mixed genetic background, heterozygotes display skeletal dysplasias with incomplete penetrance and variable expressivity; however, these skeletal abnormalities are significantly different from those observed on an coisogenic background

asymmetric sternocostal joints ( J:56661 )

• 3 of 35 heterozygotes show unilateral fusion of the 8th rib to the sternum; however, the overall number of ribs remains unchanged

abnormal thoracic vertebrae morphology ( J:56661 )

• 3 of 35 heterozygotes lack a processus spinosus on T2