Phenotypes Associated with This Genotype

Genotype
MGI:3611545

• Allelic Composition: Trp53^Bbl/Trp53⁺
• Genetic Background: C57BL/6JSfdAnu-Trp53^Bbl/Anu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:104190 )

• between 8 and 15 months of age, mice heterozygous for this mutation develop a variety of solid tumors

increased lymphoma incidence ( J:104190 )

increased T cell derived lymphoma incidence ( J:104190 )

increased fibrosarcoma incidence ( J:104190 )

increased hemangiosarcoma incidence ( J:104190 )

increased osteosarcoma incidence ( J:104190 )

increased teratoma incidence ( J:104190 )

increased brain tumor incidence ( J:104190 )

endocrine/exocrine glands

increased T cell derived lymphoma incidence ( J:104190 )

nervous system

increased brain tumor incidence ( J:104190 )

skeleton

increased osteosarcoma incidence ( J:104190 )

immune system

increased T cell derived lymphoma incidence ( J:104190 )

hematopoietic system

increased T cell derived lymphoma incidence ( J:104190 )