Phenotypes Associated with This Genotype

Genotype
MGI:3611332

• Allelic Composition: Reln^rl-6J/Reln^rl-6J
• Genetic Background: C57BL/6J-Reln^rl-6J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

tremors ( J:87349 )

• by about 3.7 weeks of age, homozygous mice exhibit a slight body tremor

muscle

muscle spasm ( J:87349 )

• from about 3.7 weeks of age, mutant mice experience brief, intermittent spasms of their hind limbs

nervous system

abnormal cerebellum development ( J:87349 )

• standard pathology examination revealed disorganization of cell layers in mutant cerebella

abnormal stratification in cerebral cortex ( J:87349 )

• standard pathology examination revealed disorganization of cell layers in the cerebral cortices of homozygous mice

small cerebellum ( J:87349 )

• standard pathology examination revealed underdevelopment of the cerebella of mutant mice