Mouse Genome Informatics
cx
    Psen1tm1Dgf/Psen1tm1Dgf
Tg(APPSWE)2576Kha/?

involves: 129 * C57BL/6 * CD-1 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• accelerated onset of amyloid deposition in a gene-dosage dependent manner
• amyloid-beta deposition was widely distributed throughout the brain and spinal cord

homeostasis/metabolism
• accelerated onset of amyloid deposition in a gene-dosage dependent manner
• amyloid-beta deposition was widely distributed throughout the brain and spinal cord

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:102425