Phenotypes for Hoxa4 Hoxb4 Hoxd4 MGI:3611055 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hoxa4^tm1Bhr/Hoxa4^tm1Bhr Hoxb4^tm1Bay/Hoxb4^tm1Bay Hoxd4^tm1Bhr/Hoxd4^tm1Bhr
Genetic Background	involves: 129S/SvEv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa4^tm1Bhr mutation (0 available); any Hoxa4 mutation (9 available)
Hoxb4^tm1Bay mutation (1 available); any Hoxb4 mutation (20 available)
Hoxd4^tm1Bhr mutation (0 available); any Hoxd4 mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal cervical vertebrae morphology ( J:27467 )

• atlas like anterior arches on C1 through C5

• lateral foramina on C2, C3, and C4

cervical vertebral transformation ( J:27467 )

• C6 to C5 and C7 to C6 transformations

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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