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Phenotypes Associated with This Genotype
Genotype
MGI:3609906
Allelic
Composition		 Shc1tm1Lex/Shc1tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shc1tm1Lex mutation (2 available); any Shc1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:103485 )
• no homozygotes seen at weaning; stage of lethality not specified

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory