About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3608125
Allelic
Composition
Bace1tm1Nn/Bace1tm1Nn
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bace1tm1Nn mutation (0 available); any Bace1 mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• exhibit impaired processing of the beta subunit of voltage-gated sodium channel (VGSC) as indicated by reduced expression of the C-terminal fragment of VGSC beta in MEFs, cerebrum, and striatum and an increase in the full length VGSC beta in striatum


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory