Analysis Tools
mortality/aging
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• similar mortality rate as homozygous Bace1tm1Psa mice, with some dying in the first 3-6 days and some by 3-4 weeks of age
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behavior/neurological
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• exhibit an increase in the time spent in open arms and an increase in the total distance traveled in elevated zero maze test
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• exhibit a significant increase in total move time and total distance traveled, however no differences in the time spent and distance traveled in the center
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