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Phenotypes Associated with This Genotype
Genotype
MGI:3606955
Allelic
Composition
Adamts13tm1Dgi/Adamts13tm1Dgi
Genetic
Background
involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts13tm1Dgi mutation (1 available); any Adamts13 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• Background Sensitivity: exhibit normal development, fertility, survival, blood smears and a similar response to shiga toxin as wildtype, even though von Willebrand Factor (vWF)-cleaving activity is lost, unlike on a background that contains CASA/Rk

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Thrombotic Thrombocytopenic Purpura, Congenital; TTP 274150 J:101752


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory