Phenotypes Associated with This Genotype

Genotype
MGI:3605232

• Allelic Composition: Efna3^tm1Rax/Efna3^tm1Rax; Efna5^tm1Ddmo/Efna5^tm1Ddmo
• Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:101720 )

• diminished survival to weaning but sufficient survivors for study

behavior/neurological

abnormal nursing ( J:101720 )

♀ • females fail to nurse young

growth/size/body

decreased body size ( J:101720 )

nervous system

abnormal olfactory bulb development ( J:101720 )

• SR1 glomeruli shifted posteriorly by about 20% of the length of the bulb and slightly ventrally on the medial aspect

• P2 glomeruli shifted somewhat posteriorly and shifted dorsally on the medial aspect