immune system
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• largely lacking in double positive cells
|
|
|
• demarcation between cortex and medulla indistinct
|
|
|
• peripheral spleen T cells 30% of control levels
|
|
|
• thymocyte production only 4.3% normal
• few proliferating thymocytes
|
|
|
• double negative cells are proportionately higher but absolute numbers are reduced
• development blocked at DN3 stage
|
hematopoietic system
|
|
• largely lacking in double positive cells
|
|
|
• demarcation between cortex and medulla indistinct
|
|
|
• peripheral spleen T cells 30% of control levels
|
|
|
• thymocyte production only 4.3% normal
• few proliferating thymocytes
|
|
|
• double negative cells are proportionately higher but absolute numbers are reduced
• development blocked at DN3 stage
|
endocrine/exocrine glands
|
|
• largely lacking in double positive cells
|
|
|
• demarcation between cortex and medulla indistinct
|
|
|
• thymocyte production only 4.3% normal
• few proliferating thymocytes
|


Analysis Tools