Mouse Genome Informatics
cn
    Gcktm1.1Mgn/Gcktm1.1Mgn
Tg(Ins2-cre)25Mgn/0

involves: 129S6/SvEvTac * C57BL/6 * DBA/2
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• more than 80% neonatal mortality as a result of severe hyperglycemia

homeostasis/metabolism
• highly variable but increased blood glucose concentrations
• decreased by about 70%
• diminished hepatic glycogen

liver/biliary system

Mouse Models of Human Disease
OMIM IDRef(s)
Maturity-Onset Diabetes of the Young, Type 2; MODY2 125851 J:51826