Mouse Genome Informatics
hm
    Gcktm1.2Mgn/Gcktm1.2Mgn
involves: 129S6/SvEvTac * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• die within 4 days of birth from severe diabetes

homeostasis/metabolism
• plasma glucose concentration of 566 mg/dl compared to 73 mg/dl in wild-type, at 2 days of age
• reduced by approximately 70%
• about 1.8-fold increase
• diminished hepatic glycogen

liver/biliary system

Mouse Models of Human Disease
OMIM IDRef(s)
Maturity-Onset Diabetes of the Young, Type 2; MODY2 125851 J:51826