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Phenotypes Associated with This Genotype
Genotype
MGI:3590138
Allelic
Composition
GckRgsc236/Gck+
Genetic
Background
involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GckRgsc236 mutation (1 available); any Gck mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• increased glycosylated hemoglobin indicating a prolonged increase in serum glucose
• mutants have a free fed serum glucose level of 200 mg/dl or more, this was the basis for selection in the ENU screen

hematopoietic system
• increased glycosylated hemoglobin indicating a prolonged increase in serum glucose

Mouse Models of Human Disease
OMIM ID Ref(s)
Maturity-Onset Diabetes of the Young, Type 2; MODY2 125851 J:88919


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory