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Phenotypes Associated with This Genotype
Genotype
MGI:3590133
Allelic
Composition		 Rigitm1Aki/Rigitm1Aki
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rigitm1Aki mutation (0 available); any Rigi mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:100539 )
• a few mice were born alive, but showed growth retardation and died within 3 weeks after birth
embryonic lethality during organogenesis, incomplete penetrance ( J:100539 )
• most homozygous embryos were dead at embryonic days 12.5 to 14.0

liver/biliary system
liver degeneration ( J:100539 )
• histological analysis of embryonic day 12.5 embryos revealed massive liver degeneration accompanied with aberrant occurrence of apoptosis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory