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Phenotypes Associated with This Genotype
Genotype
MGI:3589471
Allelic
Composition		 Col8a2tm1Bjro/Col8a2tm1Bjro
Genetic
Background		 B6.129S4-Col8a2tm1Bjro
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col8a2tm1Bjro mutation (0 available); any Col8a2 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal Descemet membrane morphology ( J:100136 )
• banded structures within the Descemet's membrane are completely absent
decreased Descemet membrane thickness ( J:100136 )
• Descemet's membrane is thinner

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory