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Phenotypes Associated with This Genotype
Genotype
MGI:3588731
Allelic
Composition
Cln8mnd/Cln8mnd
Genetic
Background
involves: B6.KB2 * C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cln8mnd mutation (2 available); any Cln8 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• Background Sensitivity: death similar to that seen on the inbred B6.KB2 background (J:1224)

nervous system
• Background Sensitivity: neurological disease progresses in a similar fashion as on the inbred B6.KB2 background
• Background Sensitivity: exhibit motor neuron disease symptoms at around 6 months of age and do not die prior to 10-12 months of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
neuronal ceroid lipofuscinosis 8 DOID:0110723 OMIM:600143
J:56219


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory