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Phenotypes Associated with This Genotype
Genotype
MGI:3587023
Allelic
Composition		 Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Nphs2-cre)1Seq/0
Tg(tetO-Vegfa)90Ala/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy mutation (5 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Nphs2-cre)1Seq mutation (0 available)
Tg(tetO-Vegfa)90Ala mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
albuminuria ( J:99607 )
• administration of doxycycline in the drinking water to 4 month old mice and consequent VEGF-A164 expression in podocyte of glomerulus caused proteinuria after 7 days of treatment

renal/urinary system
albuminuria ( J:99607 )
• administration of doxycycline in the drinking water to 4 month old mice and consequent VEGF-A164 expression in podocyte of glomerulus caused proteinuria after 7 days of treatment

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory