Phenotypes Associated with This Genotype

Genotype
MGI:3586390

• Allelic Composition: Zfpm1^tm4Sho/Zfpm1^tm4Sho; Tg(Gata1-Zfpm1)1Sho/0; Tg(Tek-cre)1Ywa/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

thin myocardium ( J:99745 )

• variably thinner than wild type but not as thin as that seen in the Zfpm1 knockout embryos

double outlet right ventricle ( J:99745 )

• observe a small degree of conal rotation, resulting in a slightly more rostral origin of the aorta from the right ventricle compared with that of the pulmonary artery

common atrioventricular valve ( J:99745 )

• have a single common atrioventricular valve

atrial septal defect ( J:99745 )

atrioventricular septal defect ( J:99745 )

ventricular septal defect ( J:99745 )

muscle

thin myocardium ( J:99745 )

• variably thinner than wild type but not as thin as that seen in the Zfpm1 knockout embryos