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Phenotypes Associated with This Genotype
Genotype
MGI:3586365
Allelic
Composition
Tg(tetO-Vegfa)90Ala/?
Tg(SFTPC-rtTA)5Jaw/?
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(SFTPC-rtTA)5Jaw mutation (5 available)
Tg(tetO-Vegfa)90Ala mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• administration of doxycycline to pregnant mother and consequent VEGF-A164 expression in peripheral respiratory epithelial cells of E10.5 to E16.5 embryo caused altered peripheral lung morphogenesis with disrupted vascular pattern formation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory