Phenotypes Associated with This Genotype

Genotype
MGI:3584499

• Allelic Composition: Rcvrn^tm1Clma/Rcvrn^tm1Clma
• Genetic Background: involves: 129S1/Sv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal eye electrophysiology ( J:99835 )

• faster flash response recovery in dark-adapted rods

• phosphodiesterase adaptation is absent in rods

• calcium dynamics are accelerated in rods in response to bright, saturating flashes of light

• electroretinograms exhibit two corneal positive b-waves rather than one in response to a single midrange scotopic flash

• sensitivity of rods to steps of lights is decreased