Mouse Genome Informatics
cn
    Emx1tm1(cre)Ito/?
Gt(ROSA)26Sortm1(HD*103Q)Xwy/?

involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
N
• mice have comparable locomotor activity to wild-type controls (J:99759)
• gliosis levels are comparable to wild-type (J:99759)
• dendrites with abnormal or wavy morphology occur with similar frequency in mutants and wild-type controls (J:99759)
• very few neurons showing early stages of degeneration are observed (J:99759)
• electrophysiology such as sIPSCs from cortical neurons are normal relative to controls (J:99759)

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Huntington Disease; HD 143100 J:99759