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Phenotypes Associated with This Genotype
Genotype
MGI:3584278
Allelic
Composition		 Ihhtm1Amc/Ihhtm2Amc
Pth1rtm1Hmk/Pth1rtm2Hmk
Tg(Bglap2-cre)1Kry/0
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ihhtm1Amc mutation (1 available); any Ihh mutation (25 available)
Ihhtm2Amc mutation (0 available); any Ihh mutation (25 available)
Pth1rtm1Hmk mutation (0 available); any Pth1r mutation (30 available)
Pth1rtm2Hmk mutation (0 available); any Pth1r mutation (30 available)
Tg(Bglap2-cre)1Kry mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal chondrocyte differentiation ( J:99641 )
• ectopic hypertrophic differentiation in growth plates, however do not observe elongation of the columnar region

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory