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Phenotypes Associated with This Genotype
Genotype
MGI:3583886
Allelic
Composition
Pou4f2tm1Rsd/Pou4f2tm1Rsd
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou4f2tm1Rsd mutation (1 available); any Pou4f2 mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• disorganized morphology specifically subtle differences in the cell density and the laminar organization that are particularly apparent in the stratum zonale
• a loss of approximately 60-70% of retinal ganglion cells in P17-P120 mice
• count profiles in the ganglion cell layer of neonatal (P0) retina are normal

vision/eye
• a loss of approximately 60-70% of retinal ganglion cells in P17-P120 mice
• count profiles in the ganglion cell layer of neonatal (P0) retina are normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory