Phenotypes for Shh MGI:3583816 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Shh^Dsh/Shh^tm1Chg
Genetic Background	involves: 101 * 129S1/Sv * 129X1/SvJ * C3H * C57BL/10Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shh^Dsh mutation (0 available); any Shh mutation (48 available)
Shh^tm1Chg mutation (2 available); any Shh mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal dorsal-ventral axis patterning ( J:97323 )

• have midline defects that are seen in the single homozygous Shh mutants

limbs/digits/tail

abnormal limb morphology ( J:97323 )

• have limb malformations that are nearly identical to that of single homozygous Shh mutants

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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