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Phenotypes Associated with This Genotype
Genotype
MGI:3583717
Allelic
Composition		 Tubg1tm1Sts/Tubg1tm1Sts
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tubg1tm1Sts mutation (0 available); any Tubg1 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:99398 )
• homozygous embryos are alive at E3.5 but die before implantation due to mitotic arrest

embryo
embryonic growth arrest ( J:99398 )
• mitotic arrest is seen in the blastocyst stage with deformed and disorganized mitotic spindles

cellular
abnormal mitotic spindle morphology ( J:99398 )
• mitotic arrest is seen in the blastocyst stage with deformed and disorganized mitotic spindles

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory