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Phenotypes Associated with This Genotype
involves: C3H * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift88Tg737Rpw mutation (0 available); any Ift88 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• Background Sensitivity: pancreatic lesions have characteristics of both parent strains; however none of the F1 and only 1 F2 had visible pancreatic cysts at the time of death

liver/biliary system
• Background Sensitivity: the liver lesion is more variable compared to mice on inbred FVB/N or C3H backgrounds

renal/urinary system
• Background Sensitivity: cyst development is intermediate compared to mice on inbred FVB/N (more severe) and C3H (less severe) backgrounds
• at 20-30 days of age, cysts are between 6.92% and 3.92% of the total kidney area

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autosomal recessive polycystic kidney disease DOID:0110861 OMIM:263200

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory