Mouse Genome Informatics
cx
    Klc1tm1Gsn/Klc1+
Tg(APP695)3Dbo/?

involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• levels of amyloid beta are consistently elevated relative to controls
• increased axonal swelling independent of amyloid deposition

homeostasis/metabolism
• levels of amyloid beta are consistently elevated relative to controls

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:96346