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Phenotypes Associated with This Genotype
involves: 101 * C3H * T STOCK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bicc1jcpk mutation (0 available); any Bicc1 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
• generally die between 7 to 10 days after birth with none surviving longer than 20 days (J:27506)

renal/urinary system
• cysts are evident at birth and increase in number and size with age (J:23047)
• cysts are initially found in the inner cortical and medullary regions, by 4 days of age cysts have expanded to involve most areas of the kidney including the outer cortex, and by 7 days virtually the entire kidney is affected (J:23047)

liver/biliary system
• about 50% of homozygotes have an enlarged gallbladder

digestive/alimentary system
• dilation of the pancreatic duct

• seen at 3 to 10 days of age

endocrine/exocrine glands
• dilation of the pancreatic duct
• about 50% of homozygotes have an enlarged gallbladder

Mouse Models of Human Disease
OMIM ID Ref(s)
Polycystic Kidney Disease, Autosomal Recessive; ARPKD 263200 J:23047

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory